Angebote zu "Integrins" (5 Treffer)

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I Domains in Integrins
192,49 € *
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I Domains in Integrins ab 192.49 EURO Auflage 2003

Anbieter: ebook.de
Stand: 06.06.2020
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Studies On the Coxsackie and Adenovirus Receptor
49,00 € *
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CAR has recently been identified as a high affinity receptor for both Coxsackievirus and certain adenovirus (AV) serotypes. Virus bound by CAR is passed to integrins which bind an RGD (Arg-Gly-Asp) sequence in the viral penton base protein and act as secondary receptors responsible for virus internalization.Recent studies have shown that, in integrin-expressing cells, CAR can directly mediate AV uptake without penton base RGD-av integrin interactions. I confirmed that EC+ transmembrane (TM) domains of CAR are sufficient for AV uptake in integrin-expressing cells.CAR is the primary AV receptor and integrins are secondary AV receptors. To investigated the possibility that these proteins associate in a functional complex in the cell membrane, I forced CAR expression in a line of human myoblasts and obtained coprecipitation of CAR and B3 integrin suggesting these proteins may associate.I also found that mouse brain extract reproducibly modifies the immunoreactivity of the CAR C-terminal fusion protein and increase its tendency to dimerize. Mouse brain extracts also modified the isoelectric pH of the CAR C-terminal fusion protein.

Anbieter: Dodax
Stand: 06.06.2020
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Diverse Roles of Integrin Receptors in Articula...
150,90 CHF *
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This review focusses on the expression and function of ss1-integrins in articular chondrocytes. The authors discuss the research carried out over the last 20 years in their own laboratories and in the laboratories of others involved in studying chondrocyte ECM adhesion and signal transduction. TOC:Introduction.- Integrins - multifunctional adhesion molecules.- Integrin structure-function relationships.- Structure of integrins.- EGF domains in ss1-integrins.- Integrins in articular cartilage.- Monolayer cultures.- High density (organoid-) cultures.- Concluding remarks.- Acknowledgements.- References.- Subject index.

Anbieter: Orell Fuessli CH
Stand: 06.06.2020
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Diverse Roles of Integrin Receptors in Articula...
121,00 € *
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This review focusses on the expression and function of ß1-integrins in articular chondrocytes. The authors discuss the research carried out over the last 20 years in their own laboratories and in the laboratories of others involved in studying chondrocyte ECM adhesion and signal transduction. TOC:Introduction.- Integrins - multifunctional adhesion molecules.- Integrin structure-function relationships.- Structure of integrins.- EGF domains in ß1-integrins.- Integrins in articular cartilage.- Monolayer cultures.- High density (organoid-) cultures.- Concluding remarks.- Acknowledgements.- References.- Subject index.

Anbieter: Thalia AT
Stand: 06.06.2020
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