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The function and regulation of chick Ebf genes ...
79,00 € *
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The three chick Ebf (Early B-cell Factor) genes are members of EBF helix loop helix transcription factors. EBFs have been characterised for their roles in differentiation of B-lymphocytes and neural cells.Recently,a new role for some EBFs in bone development has been investigated. However,their expression profile and regulation in the somites (axial skeleton precursor) have yet to be elucidated. I have found cEbf somitic expression in medial (cEbf1) and lateral (cEbf2 and cEbf3) sclerotomal domains and later around vertebral cartilage anlagen of body,pedicles (cEbf1) and arch (cEbf2 and cEbf3).I have presented a model in which expression cEbf1 is initiated by low dose of BMP4 from lateral mesoderm and maintained by Shh from notochord.However, the other two chick Ebf genes are induced by BMP4 and inhibited by high dose of Shh.I have also found that cEbf1 can induce other sclerotomal markers,Pax1 and Sox9,and dermomyotomal marker,MyoD,but antagonises lateral markers,cEbf3 and Pax3.Thus,cEbf1 is a sclerotomal marker expressed in axial skeletogenic tissues under control of Shh and Bmp4 and that this expression is crucial for sclerotome development and mediolateral patterning of somites.

Anbieter: Dodax
Stand: 03.06.2020
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Wilson, J: Node.js the Right Way
19,90 CHF *
zzgl. 3,50 CHF Versand

Get to the forefront of server-side JavaScript programming by writing compact, robust, fast, networked Node applications that scale. Ready to take JavaScript beyond the browser, explore dynamic languages features and embrace evented programming? Explore the fun, growing repository of Node modules provided by npm. Work with multiple protocols, load-balanced RESTful web services, express, 0MQ, Redis, CouchDB, and more. Develop production-grade Node applications fast. JavaScript is the backbone of the modern web, powering nearly every web app's user interface. Node.js is JavaScript for the server. This book shows you how to develop small, fast, low-profile, useful, networked applications. You'll write asynchronous, non-blocking code using Node's style and patterns. You'll cluster and load balance your services with Node core features and third-party tools. You'll work with many protocols, creating RESTful web services, TCP socket clients and servers, and more. This short book packs a hefty dose of Node.js. You'll test your code's functionality and performance under load. You'll learn important aspects of Node development--from its architecture and core, to its ecosystem of third-party modules. You'll discover how Node pairs a server-side event loop with a JavaScript runtime to produce screaming fast, non-blocking concurrency. Through a series of practical programming domains, you'll use the latest available ECMAScript Harmony features and harness key Node classes such as EventEmitter and Stream. Throughout the book, you'll develop real programs that are small, fast, low-profile, and useful. Get ready to join a smart community that's rapidly advancing the state of the art in web development. What You Need: Latest stable release of Node.js, this book was written with 0.12.x in mind.The 0MQ (ZeroMQ) library, version 3.2 or higher.

Anbieter: Orell Fuessli CH
Stand: 03.06.2020
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The function and regulation of chick Ebf genes ...
134,00 CHF *
ggf. zzgl. Versand

The three chick Ebf (Early B-cell Factor) genes are members of EBF helix loop helix transcription factors. EBFs have been characterised for their roles in differentiation of B-lymphocytes and neural cells.Recently,a new role for some EBFs in bone development has been investigated. However,their expression profile and regulation in the somites (axial skeleton precursor) have yet to be elucidated. I have found cEbf somitic expression in medial (cEbf1) and lateral (cEbf2 and cEbf3) sclerotomal domains and later around vertebral cartilage anlagen of body,pedicles (cEbf1) and arch (cEbf2 and cEbf3).I have presented a model in which expression cEbf1 is initiated by low dose of BMP4 from lateral mesoderm and maintained by Shh from notochord.However, the other two chick Ebf genes are induced by BMP4 and inhibited by high dose of Shh.I have also found that cEbf1 can induce other sclerotomal markers,Pax1 and Sox9,and dermomyotomal marker,MyoD,but antagonises lateral markers,cEbf3 and Pax3.Thus,cEbf1 is a sclerotomal marker expressed in axial skeletogenic tissues under control of Shh and Bmp4 and that this expression is crucial for sclerotome development and mediolateral patterning of somites.

Anbieter: Orell Fuessli CH
Stand: 03.06.2020
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The function and regulation of chick Ebf genes ...
71,99 € *
ggf. zzgl. Versand

The three chick Ebf (Early B-cell Factor) genes are members of EBF helix loop helix transcription factors. EBFs have been characterised for their roles in differentiation of B-lymphocytes and neural cells.Recently,a new role for some EBFs in bone development has been investigated. However,their expression profile and regulation in the somites (axial skeleton precursor) have yet to be elucidated. I have found cEbf somitic expression in medial (cEbf1) and lateral (cEbf2 and cEbf3) sclerotomal domains and later around vertebral cartilage anlagen of body,pedicles (cEbf1) and arch (cEbf2 and cEbf3).I have presented a model in which expression cEbf1 is initiated by low dose of BMP4 from lateral mesoderm and maintained by Shh from notochord.However, the other two chick Ebf genes are induced by BMP4 and inhibited by high dose of Shh.I have also found that cEbf1 can induce other sclerotomal markers,Pax1 and Sox9,and dermomyotomal marker,MyoD,but antagonises lateral markers,cEbf3 and Pax3.Thus,cEbf1 is a sclerotomal marker expressed in axial skeletogenic tissues under control of Shh and Bmp4 and that this expression is crucial for sclerotome development and mediolateral patterning of somites.

Anbieter: Thalia AT
Stand: 03.06.2020
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